Antidepressants is a sensitive matter. Many people are prescribed the drugs because of their health condition, but we all know that some of the drugs have the abuse potential. You are not allowed to buy such antidepressants like Sertraline (Zoloft) without prescription by the government, but if you try, you can always get a dozen or two of the pills via online pharmacies and from other sources. Some people are intended to abuse the drugs, saying something like “Zoloft makes me feel high”, or “Zoloft get you high”, and considering that relatively safe and effective. Well, there are better ways to get high for sure, as it will be shown in this article.
Zoloft belongs to the SSRI class of drugs. The abbreviation stands for selective serotonin reuptake inhibitors, and it describes the mechanism of action of such drugs. Inhibiting the serotonin transporter, the active substance in such medications prevents serotonin molecules from being absorbed, thus increasing the concentration of free serotonin molecules in brain. Serotonin is responsible for feeling of happiness and comfort, and some drugs stimulate the secretion of that hormone to get you high. However, there is a huge difference between SSRI and the drugs that affect the production of serotonin. With SSRI, you won't usually have higher amounts of the hormone than normal. That's why the medication is prescribed to people who have clinical depression: their serotonin levels are abnormally low, which has a serious impact on the quality of life. Zoloft gets them back to normal, but rarely better than that.
But... what if you increase the dosage? If a pill of Zoloft can make the depression go, maybe a couple of them can make the happiness come? Unfortunately, it's not true. Typically, patients have to take the medication for weeks to notice a positive effect of their therapy. Too high Zoloft dosage will definitely give you a bunch of side effects, associated with this medication, but almost never get you higher than you are. Of course, it depends on your individual tolerance to the drug. One of a thousand patients, approximately, reports that he has gotten high on Zoloft, just taking his usual dose. In this case, “high” can mean “much better than usual”, which isn't something outstanding for a patient with severe depression. People who have normal levels of serotonin in brain, will rarely see the difference.
While it's hard to get high on Zoloft, it's much easier to get adverse effects from such experiments. If you overdose the medication, Zoloft high blood pressure side effect may pop up, making you suffer from the immature decisions. Nausea and vomiting won't be very pleasant too, you can trust me. If you're getting to far beyond reason and the normal dose of Zoloft, you may die, which is not something you'd associate with getting high. Try snorting Zoloft high, and you'll know what it's worth.
The bottom line of this short guide of getting high on Zoloft is: it doesn't worth it. Taking a horse dose of Sertraline to experience a weak euphoric effect for a while and side effects of the drug for a week is definitely not something you aim to achieve. Perhaps, you should look for other drugs, more addictive than Zoloft, or get high like the smart people do: enjoying sports, relationship, art and other healthy things.